Leading gene-editing biotechs CRISPR Therapeutics and Intellia are likely to be acquired at some point. BioNTech Strengthens Its Artificial Intelligence With Acquisition Of British . Editor's note: If tables or values do not display, please try clearing your browser's cache and reloading the page. RTTNews.com for All rights reserved. PwC also expects large-sized deals, valued at $50 billion or more, for diversifying into adjacent therapeutic areas. Abbott Laboratories bought out Solvay Pharmaceuticals for $6.1B. 2. Whether M&A activity continues will have a significant effect on which startups and drug programs get funded and advanced. According to Glenn Hunzinger, U.S. Pharmaceutical & Life Sciences Consulting Solutions Leader at PricewaterhouseCoopers. BioMarin(NASDAQ:BMRN) focuses on gene therapies, one of the most recent treatment paradigms that promise huge scope for treating serious and life-threatening genetic disorders. A company with an approved cancer drug for two different indications and a very promising clinical research pipeline with a market capitalization of only $183.3 million? But Alnylam's study isn't the only major readout expected this year for a genetic heart condition that's become a top target for many drugmakers. Dan Cohen is a partner at stockmatusow and entrepreneur in the fields of nanotechnology, medical diagnostics, and energy storage. Many times in recent years, premiums on biopharma acquisitions surpassed 100%. Go and get our Biotech Investments HOT STOCK REPORT. *Premiums are calculated from the closing price of the acquired company's shares on the previous trading day. The companies are already partners for CRISPR's beta-thalassemia and sickle cell therapy. Just briefly, very quickly, I think Biogen (BIIB 0.54%) needs to make an acquisition -- ticker for Biogen is BIIB. Learn More. In case of a buyout, investors often benefit of a massive premium. 3. Shanthi is a contributor to InvestorPlace.com as well as a staff writer with Benzinga. The report, out from financial news wire Bloomberg, said the California biotech "is exploring a sale and has held preliminary talks with potential buyers, according to people familiar with the matter." Hunzinger said: Biotech and smaller medical device deals should continue in the first half of the year, with the second half poised for larger deals driven by a need for scale and an expected settling of the regulatory landscape.. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Brian, what are some acquisitions that you'd like to. Additional disclosure: Disclaimer: This article is intended for informational and entertainment use only, and should not be construed as professional investment advice. PDP is a wide open unmet need market, currently with no treatments on the market. Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech partners. Sold Kos Pharmaceuticals to Abbott Laboratories: Mr. King served as Executive Vice President of Commercial Operations of Kos Pharmaceuticals, Inc. See above section for details on that buyout. This apart, the company has a host of investigational medicines in development for DMD. Keith Speights owns shares of Vertex Pharmaceuticals. It has three FDA-approved therapies in Exondys 51, Vyondys 53 and Amondys 45, all of which are used to treat Duchenne muscular dystrophy (DMD). In 2016, Forbes listed Alnylam on its 100 Most Innovative Growth Companies. Companies, mergers and acquisitions Gland Pharma India Pharmaceutical Torrent Pharmaceuticals. RTTNews->. Use a + to require a term in results and - to exclude terms. 10. There's a company called Adicet Bio (ACET 0.46%), ticker there is ACET, I believe. I wrote this article myself, and it expresses my own opinions. However, late in the month, Bristol-Myers Squibb announced it had inked a deal with Amgen over its Otezla. Nasdaq AMRN closed Friday's trading at $24.12, up 4.92%. Over the last few years, pharmaceutical M&A hit record highs as larger companies turned again and again to young biotechs for innovation. Intercept Pharma(NASDAQ:ICPT), a company focused on non-viral liver diseases, is a risky M&A target because it is a one-trick pony. ALXN is down 22% from its all-time high of $141.86, recorded on April 10, 2019, and trades around $110. Sold Sepracor to Dainippon Sumitomo: Mr. Adams served as President and Chief Executive Officer of Sepracor Inc. Dainippon Sumitomo bought out Sepracor for $2.6B, or a 48% premium over the current share price. Targeted indications include cardio-renal, metabolic, neurological, infectious diseases, cancer, ophthalmology, pulmonary & allergy and hematology. Often, these deals focused on cancer, rare diseases and immune system disorders areas of drug research that were seeing major victories in clinical trials and huge profits for treatments that made it to market. BioMarin is almost every analyst's favorite takeover candidate. It seems like the same team has assembled again to eventually sell AcelRx for a nice premium. Sarepta (NASDAQ:SRPT) is a precision medicine company developing therapies to treat rare diseases. These target KRAS mutations, which are found in about 25% of cancer patients are said to be undruggable. Premiums were calculated using the acquired company's share price at the previous trading day's close, Only one therapeutic category is counted for each acquired company. After a rather bumpy start with disappointing sales numbers in 2019 and 2020, CAPLYTA net product revenues for the second quarter 2022 showed a 190% increase as compared to the same period in 2021 and a 58% increase over the first quarter 2022. Highly anticipated study results are expected in Alzheimers, obesity and Huntingtons, while a pair of high-priced acquisitions could be put to the test. Considering its massive potential, Axsome Therapeutics it is likely to be ranked high on the shopping list of many large pharmaceutical companies for possible acquisition. There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. At the time, I was contacted by a former investment banker who stated to me that he heard there would be an eventual deal with Antares and that it was "a done deal, but the deal has not been done." Below you can find the official Biotech Investments M&A and takeover list containing some of the hottest takeover targets in biotech industry for H2 2022. Many of today's most influential medicines, from the life-saving cancer treatment Keytruda to the anti-inflammatory agent Humira, might not have become so without mergers and acquisitions. M&A strategy gives the acquiring companies a chance to grow revenue, improve efficiency and increase shareholder returns. "Human natural killer cell" [Micrograph]. On June 14, Alnylam announced that the FDA approved its RNAi drug AMVUTTRA (vutrisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults, a rapidly progressive and fatal disease with debilitating polyneuropathy manifestations for which there are few treatment options. In September, the rumor mill kept its employees working overtime by reporting that international pharmaceutical juggeraut Roche ( RHHBY -1.10%) was trying to arrange $15 billion in financing to. The stock has rallied from a little over $1 a share to a current price of $28.84, which represents an increase of over 2800% - a staggering number. Biotech companies have had an easy time raising huge sums of money from private investors and, until recently, the public markets. Pharma giant Pfizer recently announced that it will acquire Arena Pharmaceuticals for $100 per share or a total equity value of approximately $6.7 billion to further expand its portfolio. Miratis sitravatinib is being evaluated in two late-stage combination studies to stimulate bodys immune response to fight cancer. Invest better with The Motley Fool. In the 3rd quarter call, Jack Howarth stated that Antares approached Pfizer looking to collaborate with them. Its lead product candidate, pimavanserin, designed to treat Parkinson's Disease Psychosis (PDP) has completed a. e have heard similar buzz over the last few months, and as mentioned, the buzz makes sense to us, in no small part because Acadia has had quite an epic stock run over the last year. This conference call is no longer online, but the. In addition, the American company has several commercial and research successes, including recent positive Phase 3 clinical trial data for its ATTR amyloidosis drug ONPATTRO (Patisiran). Stay on top of what's happening at JPM. You can see the complete list of todays Zacks #1 Rank (Strong Buy) stocks here. *Average returns of all recommendations since inception. Keith Speights: All right, Brian. Acelrx's Nanotab tech could potentially grab a significant piece of this market. Subsequent letters and public pressure from Voce eventually lead to the Obagi Acquisition. The acquisition will provide Sanofi access to Amunix Pro-XTEN, XPAT and XPACT technology, complementing Sanofis existing R&D platforms. No. On June 24, BioMarin has received a positive opinion by the European Committee for Medicinal Products for Human Use (CHMP) for its gene therapy ValRox to treat adult patients with severe Hemophilia A. After a lengthy drought, could biotech M&A be on the upswing? Below you can find the official Biotech Investments M&A and takeover list containing some of the hottest takeover targets in biotech industry for H2 2022. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. Always do your own due diligence before buying and selling any stock, and/or consult with a licensed financial adviser. Takeover rumors initially swirled around Clovis Oncology in 2013 when Rubraca, was in clinical trial stage. Copyright Biotech Investments 2022 | Switzerland | All rights reserved. Now, it is three years since the PARP inhibitor has been approved. The FDA decision on Pemigatinib is expected by May 30, 2020. Orelli: I think a pharma that wanted a lot of cash flow, but also wanted to boost up their pipeline, Vertex probably has more external deals than it has internal candidates. Calyxt, Inc. (Nasdaq: CLXT), a plant-based synthetic biology company, and Cibus, a leader in precision gene editing in agriculture, today announced that both companies have entered into a definitive merger agreement under which Calyxt and Cibus will merge in an all-stock transaction. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. But following Gilead's decision to acquire Kite Pharma in August of that year, the rumors died down. Dear MULN Stock Fans, Brace Yourself for a Reverse Stock Split, 5 Under-the-Radar Penny Stocks With 100% Upside Potential, 3 Stocks Set to Soar When the Bears Get Short-Squeezed, 3 Troubled Tech Stocks to Buy For The Long Haul, 3 AI Stocks That Will Make You Amazingly Rich in 10 Years, Attractive & promising pipeline/technology. They also have a partnership for some pre-clinical products, which I think if Vertex made the acquisition, it could accelerate that and put that as a higher priority. The successful development and commercialization will significantly boost ADAP and make it an attractive buyout candidate. Item 3.01 Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing. The other candidates in the pipeline include CTX110, CTX120 and CTC130, all for immuno-oncology indications. AMAG Pharmaceuticals (Market Cap $0.7bn) US specialty firm AMAG Pharmaceuticals Inc. is viewed as an acquisition target for companies established in women's health - specifically Novartis AG - due to the potential of bremelanotide in hypoactive sexual desire disorder (HSDD). Antares Pharma (ATRS). The company has already seven products on the market. Clovis leading drug Rubraca (rucaparib), a poly (ADP-ribose) polymerase (PARP) inhibitor, has been approved by the FDA for the treatment of ovarian and prostate cancer. Founded in 1993 by brothers Tom and David Gardner, The Motley Fool helps millions of people attain financial freedom through our website, podcasts, books, newspaper column, radio show, and premium investing services. Team StockMatusow.com research and writers are: Scott Matusow; Team Leader, owner and founder of StockMatusow.com and Dan Cohen, partner, and independent investor/scientist/inventor/trader and lead contributor at stockmatusow.com. BioNTech SE (Nasdaq: BNTX, "BioNTech") and InstaDeep Ltd. ("InstaDeep") today announced that they have entered into an agreement under which BioNTech will acquire InstaDeep, a leading global technology company in the field of artificial intelligence ("AI") and machine learning ("ML"). Srpt ) is a contributor to InvestorPlace.com as well as a staff writer with Benzinga Therapeutics and are. At JPM same team has assembled again to eventually sell AcelRx for a nice.! Is three years since the PARP inhibitor has been approved, what are some acquisitions that you & # ;! Acquisitions biotech acquisition rumors you & # x27 ; d like to Nanotab tech could potentially grab a piece... 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biotech acquisition rumors